Jul 2026
Abstract P10: Early Immunosuppressive Landscape Shaped by BRCA1/p53 Loss in Early Pre-Malignant Mammary Glands Permits Tumor Development
This study establishes a stepwise model of immune remodeling preceding TNBC onset and uncovers macrophage-centered signaling as a mechanistic axis linking genetic instability to a tumor-permissive niche.
Luqi Huang, J. A. Miller, Hanisah Mk et al.
· Cancer Research · 0 citations