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Review Open access Aug 2026

Reversible vs. Irreversible Neuronal Injury in Brain Ischemia: Role of the Mitochondrial-Synaptic Axis.

Ischemia-reperfusion (I/R) injury triggers a rapid and self-amplifying cascade of mitochondrial dysfunction, synaptic instability, and neuroinflammation that ultimately determines neuronal survival and functional recovery. Early bioenergetic collapse-driven by mitochondrial depolarization, Reactive oxygen species (ROS)...

K. Yoo, Bo Hyun Jung, J. Ahn et al. · 0 citations

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