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Review Open access Sep 2026

366. The role of candidate biomarkers and biological factors in the diagnostic and statistical manual

Abstract Background The Diagnostic and Statistical Manual of Mental Disorders (DSM) has historically relied on phenomenological, symptom-based descriptions to define psychiatric disorders. Advances in neuroscience and biomarker research offer the potential to ground diagnostic categories in biological mechanisms, yet v...

M. Kas, B. Cuthbert, O. Ajilore et al. · 0 citations
Aug 2026

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression.

PURPOSE/BACKGROUND Pharmacogenomics (PGx), or the use of genetic information to assess drug-gene interactions, is an important step toward precision medicine. It is unclear if clinician use of PGx yields better outcomes for their patients. This study compared the effectiveness of combinatorial PGx-guided plus guideline...

A. Nierenberg, Masoud Kamali, Dustin J. Rabideau et al. · 0 citations

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