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Open access Sep 2026

A PVH-to-parabrachial BDNF circuit mediates non-aversive feeding suppression

Parabrachial nucleus (PBN) CGRP neurons mediate aversive feeding suppression, but PBN circuitry governing homeostatic, non-aversive feeding suppression remains poorly understood. Here, we identify a circuit in which paraventricular hypothalamus (PVH) neurons innervate BDNF-expressing ventrolateral/dorsolateral PBN (vl/...

Juan-Ji An, Ji-Wei Tan, Yu-Ting Chen et al. · 0 citations
Open access Sep 2026

Sexual dimorphism of autism-like phenotypes in microglial eIF4E overexpression mice

It is demonstrated that sex hormones are a major determinant of the increased susceptibility of males to ASD-like phenotypes in MG4E mice and the absence of ER expression in microglia suggests that sex hormones may act indirectly through hormone- responsive neurons to regulate microglia-neuron interactions during neuro...

Chang-Ran Niu, Juan-Ji An, Hannah V. Masterson et al. · 0 citations

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