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From patient-reported outcome scores to clinical meaning: defining thresholds for clinical importance for the EORTC QLQ-PR25 questionnaire for patients with prostate cancer.
This study provides the first TCIs for a questionnaire assessing health-related quality of life in patients with PCa, and may improve interpretation of individual patient scores, support symptom screening and clinical decision-making, and facilitate the definition of clinically meaningful outcomes in clinical research.
Which quality of life issues are important to patients with metastatic breast cancer: Phase 1 and 2 development of European Organisation for Research and Treatment of Cancer metastatic breast cancer module (EORTC QLQ-MBR)
Background Metastatic breast cancer (MBC) remains a treatable, but incurable disease. Anti-cancer treatments and supportive therapies aim to control disease, prolong survival, ameliorate physical symptoms and improve quality of life (QoL). Currently, no validated MBC-specific patient-reported outcome measures exist, an...