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Open access Sep 2026

Newly identified COPD GWAS protein interactors reveal a potential disease network module

Background Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous disease influenced by genetic and environmental factors. However, the interactions between COPD risk genes and their collective role in COPD susceptibility remain largely elusive. We hypothesize that the protein-protein interaction (PPI...

D. Deritei, H. Inuzuka, Cheng-Yue Zhang et al. · 0 citations
Open access Aug 2026

Cascading damage to Candida albicans cells through thioredoxin reductase loss

It is proposed that metabolic pathway competition for this shared intermediate between NADPH production and cell wall glucan biosynthesis underlies the cell wall weakness of TRR1-depleted cells, and decreased activity of a key UDP-glucose biosynthetic enzyme supports this mechanism.

Wan-Jun Qi, Udita Roy, Chun-Hui Cai et al. · 0 citations

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