Review
Open access
Oct 2026
Trends in optimizing antibacterial cationic amphiphiles
Abstract Cationic amphiphiles are investigated as antibacterials, yet their potential is often limited by host-cell toxicity. Bacterial and mammalian membranes share core physicochemical features that promote interactions with cationic amphiphiles. Selectivity is realistically understood as a relative property window....
Oladapo J. Olaosebikan, J. Babalola, L. H. Urner
· Biological chemistry · 0 citations