Author

J. Brasen

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Open access Sep 2026

Insights Into the Interplay Between the Senescent Cells and Immune Cells

Aging kidneys exhibit accumulation of senescent cells together with sterile low‐grade inflammation. However, the spatial organization of senescence‐associated immune cell accumulation in the aging kidney remains poorly defined. We systematically analyzed kidneys from young, middle‐aged, and aged mice, focusing on the s...

Martin Jaros, Marco Schmidt, L. Neubert et al. · Aging Cell · 0 citations

Open access Jul 2026

Treatment response to daratumumab in antibody-mediated kidney allograft rejection: evidence from serial protocol biopsies

ABSTRACT Background Antibody-mediated rejection (ABMR) is a major cause of chronic allograft dysfunction and graft loss after kidney transplantation (KTx). Daratumumab, antibody targeting the transmembrane glycoprotein CD38 (cluster of differentiation) on immune cells, has shown promise in the treatment of refractory A...

N. Kanzelmeyer, M. Verboom, M. Hallensleben et al. · Clinical Kidney Journal · 0 citations