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Author

J. Breitner

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Jul 2026

Early treatment with naproxen alters hippocampal metabolites in the TgF344-AD rat model of Alzheimer's disease.

The findings support the use of MRS as a useful non-invasive method of monitoring treatment-related changes in neurochemistry in transgenic animal models and highlight the possibility that earlier naproxen intervention could have distinct neurochemical effects compared to delayed treatment.

Caitlin F. Fowler, Elena Osipyan, Gabriel A. Devenyi et al. · 0 citations
Open access Aug 2026

CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer’s disease

Findings identify complement dysregulation, especially involving C1q, as an early correlate of tau-linked synaptic pathology, and support a role for complement activation in the AD molecular cascade.

J. Loncke, M. Savard, C. Picard et al. · 0 citations

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