Author

J. Brugarolas

2 papers indexed here

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Open access Sep 2026

36 Clear Cell Renal Cell Carcinoma Consensus Transcriptomic Programs Reveal Converging Trajectories Towards Aggressive Disease

Abstract Background Clear cell renal cell carcinoma (ccRCC) is characterized by a branching genomic architecture in which biallelic VHL inactivation is followed by divergence into PBRM1- or BAP1-mutant lineages, with subsequent acquisition of additional alterations contributing to progression and aggressive behavior. H...

Roy Elias, Vivek Nimgaonkar, B. Xie et al. · The Oncologist · 0 citations

Open access Sep 2026

Clinical Outcomes, Treatment Patterns, and Molecular Heterogeneity of TFE3‐Rearranged Renal Cell Carcinoma: A Multicenter Real‐World Study

TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is uncommon and encompasses biologically diverse tumors, while evidence to guide systemic treatment remains sparse. We examined clinical outcomes, treatment patterns, and molecular features in a multicenter real‐world cohort.

Shu-Xuan Zhu, Si-Qi Zhou, Xi Tian et al. · Cancer Medicine · 0 citations