J. Bruun

Abstract B042: Pharmacophenotypic analysis of advanced pancreatic cancer patient-derived tumoroid models uncovers spatiotemporal drug resistance dynamics associated with single-agent and combination therapies

Despite decades of intensive research, pancreatic cancer remains one of the deadliest malignancies, with only modest improvements in patient survival. Recently, important clinical breakthroughs have been achieved with inhibitors targeting the active RAS(ON) state, doubling the median overall survival of patients...