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J. Burgoyne

1 paper indexed here

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Open access Aug 2026

Targeting PKGIα Cys42 attenuates cardiac dysfunction in heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent condition associated with substantial morbidity and mortality, yet effective therapeutic options remain limited. As oxidation of Cys42 in cyclic guanosine monophosphate (cGMP)-dependent protein kinase Iα (PKGIα) can enhance vessel and diastoli...

J. Su, Yue Zhao, Pierre Coleman et al. · 1 citation

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