In Luminal A breast cancer, bulk FOXC1 reports the tumour vasculature, while a proliferation-independent basal-lineage axis marks the tumour cells
FOXC1 is widely interpreted as a tumour-cell driver of basal identity and immune phenotype in breast cancer, including within the Luminal A (LumA) subtype, where its bulk expression tracks basal-like features and immune infiltration. Because LumA tumours are compositionally heterogeneous, whether this reflects malignan...