Distinct Transcriptional Programs Controlled by NR5A1 and β-Catenin in Adrenocortical Carcinoma
The modulation patterns associated with CTNNB1 and CTNNBIP1, together with the repression of NR5A1 regulon activity following cBAF inhibition, raise the possibility that NR5A1 acts as a context-dependent regulatory node connecting oncogenic signaling and chromatin-remodeling mechanisms in ACC.