J. Chabalgoity

Attenuated Salmonella as a modulator of the cancer–immunity cycle: from innate activation to adaptive antitumor memory

Attenuated engineered strains of Salmonella have emerged as promising tools in cancer immunotherapy due to their intrinsic tumor-targeting properties and their ability to reshape the tumor immune microenvironment. Beyond their direct cytotoxic effects on tumor cells, Salmonella profoundly modulates both innate and adap...