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J. Collier

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Open access Aug 2026

Multi-omics approaches reveal direct NF-κB p65 target genes in pancreatic islets during cytokine exposure and in Type 1 diabetes

Findings clearly show that IL-1β signaling in pancreatic β-cells directs p65 to specific genomic regions congruent with increased gene expression relevant to T1D in β-cell lines as well as mouse and human islets exposed to cytokines.

Thomas M. Martin, Susan J. Burke, Heidi M. Batdorf et al. · 0 citations

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