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Open access Oct 2026

Bypass of the canonical biotin synthesis pathway in yeast.

Biotin serves as an essential cofactor for several carboxylation enzymes that catalyze reactions vital for cell survival and proliferation. While bacterial biotin synthesis pathways are well characterized, the mechanisms in eukaryotic organisms remain poorly understood. In Saccharomyces cerevisiae, Bio1 catalyzes the i...

Rayeed M. Ihsan, J. Cronan · 0 citations

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