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J. D. Mougous

2 papers indexed here

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Open access Oct 2026

The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

Bacteria inhabiting the mammalian gut coexist in dense communities where contact-dependent antagonism mechanisms are widespread. The type VI secretion system (T6SS) is an interbacterial toxin delivery pathway prevalent among gut Bacteroidales, yet its function in naturally evolved microbiomes remains poorly defined. He...

Beth A. Shen, K. Asfahl, Bentley Lim et al. · 0 citations
Open access Sep 2026

Oral Actinobacteria sense and defend against parasitic epibionts

It is shown that Actinomycetota fend off Patescibacteria using the Esx secretion system and that this response occurs at the transcriptional level and is mediated by a previously undescribed threat sensing pathway whose activation leads to threonine phosphorylation of an FHA domain-containing output protein.

Ya-Xi Wang, Jake Colautti, Larry A. Gallagher et al. · 1 citation

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