Antiviral profile of hepatitis B virus capsid assembly modulator ALG-001075, the parent of pevifoscorvir sodium.
Chronic hepatitis B virus (HBV) infection remains an important unmet medical need with 240 million patients worldwide. The HBV capsid assembly process has emerged as a key target for more efficient antiviral intervention. Pevifoscorvir sodium (ALG-000184), an oral prodrug of the potent HBV capsid assembly modulator (CA...