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J. Dominguez

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Open access Aug 2026

Transcriptomic profiling identifies tumor necrosis factor receptor-associated factor (TRAF)-5 expression in human atherosclerotic plaques as a predictor of future cardiovascular events.

AIM OF THE STUDY Tumor necrosis factor receptor-associated factors (TRAFs) are cytoplasmic adapter proteins that regulate immune cell signaling downstream of TNF, interleukin-1, and Toll-like receptors. Although preclinical data implicate TRAFs in atherogenesis, their clinical relevance in human disease remains unknown...

M. Gissler, Xin Gu, F. V. D. van der Zalm et al. · 0 citations

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