Author

J. Fellay

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Open access Sep 2026

Characterization and Applications of the Protein Corona Forming on the Naturally Occurring Nanoparticles, Low-Density Lipoproteins

Low-density lipoproteins (LDL) are naturally occurring, monodisperse nanoparticles composed of proteins and lipids with an average diameter of 18–25 nm. Their biological functions such as cholesterol trafficking and their role in various diseases have been extensively studied. However, their properties as nanoparticles...

Ding-Hong Ren, Li-Xia Wei, Simon Boutry et al. · ACS Central Science · 0 citations

Open access Jul 2026

Mutational bias shapes protein evolution across RNA viruses

A nearly neutral framework that translates nucleotide mutational spectra into expected amino acid substitution patterns and equilibrium amino acid compositions indicates that departures from the nearly neutral baseline provide a quantitative proxy for purifying and positive selection.

B. Efimenko, Alexander Voronka, Victoriya Skripskaya et al. · bioRxiv · 1 citation

Open access Aug 2026

Benchmarking large language models for HIV medical decision support

HIVMedQA is developed, a clinician-curated benchmark of HIV-related open-ended medical question-answer pairs spanning basic knowledge, clinical reasoning, complex patient vignettes, and bias-modified scenarios that provides a structured benchmark for evaluating LLMs in HIV clinical decision support.

Gonzalo Cardenal-Antolin, J. Fellay, Bashkim Jaha et al. · Communications Medicine · 1 citation