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J. Fiehler

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Open access Sep 2026

A comparative study of causal machine learning models for personalized treatment of acute ischemic stroke

Accurate estimation of the individualized treatment effect (ITE) is critical for supporting personalized decision-making in acute ischaemic stroke, while the average treatment effect (ATE) provides a cohort-level benchmark for method comparison and context. However, the consistency and reliability of different ca...

Vahid Farmani, H. Kniep, M. Maros et al. · 0 citations
Sep 2026

Sensitivity of Non-contrast Computed Tomography Net Water Uptake Versus FLAIR-MRI, with MR-DWI Reference Standard, for Early Detection and Physiological Characterization of Ischemic Edema in Hyperacute Stroke.

OBJECTIVE On non-contrast computed tomography (NCCT), progressive hypoattenuation can be quantified as percent net water uptake (%NWU), whereas relative fluid attenuated inversion recovery (rFLAIR)-magnetic resonance imaging hyperintensity marks later-stage vasogenic edema and blood-brain-barrier disruption. We compare...

Gabriel Broocks, A. Kemmling, René Werner et al. · 0 citations
Open access Sep 2026

Quantitative assessment of cerebral venous outflow on routine CT angiography in acute ischemic stroke.

OBJECTIVES To develop and validate a semi-automated, observer-independent method for quantitative assessment of cerebral venous outflow on routine single-phase CT angiography (CTA) in acute ischemic stroke. MATERIALS AND METHODS In this multicenter retrospective study, patients with anterior circulation large-vessel...

T. Faizy, H. van Voorst, G. Albers et al. · 0 citations
Open access Jul 2026

Preoperative tumor cerebral blood flow measured by arterial spin labeling predicts enhancing tumor volume progression in gliomas: a single-center retrospective study

Arterial spin labeling (ASL) enables non-invasive quantification of cerebral blood flow (CBF). The preoperative prognostic value of tumor-specific CBF for subsequent enhancing tumor (ET) volume progression in gliomas remains poorly characterized. In this study 60 glioma patients (predominantly glioblastoma, WHO grade 4...

T. Lindner, J. Fiehler · 0 citations

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