Author

J. Fierstra

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Review Open access Sep 2026

EXPRESS: BOLD Contrast in Cerebral Diffuse Glioma Imaging: Biological Foundations and Clinical Applications - A Review of the Literature.

Diffuse cerebral gliomas are the most common malignant brain tumors in adults. In the present work we conducted a narrative review on the role of blood oxygen level-dependent (BOLD)-MRI in diffuse glioma imaging, from historical and clinical applications to recent translational studies including approaches to detect va...

Felice Strangis, T. Schmidlechner, E. Jehli et al. · Journal of Cerebral Blood Fl... · 0 citations

Open access Aug 2026

Beyond the Initial Ictus: Timing of WFNS Grade Assessment and Outcome Prediction in Aneurysmal Subarachnoid Hemorrhage.

BACKGROUND To identify the clinical timepoint of World Federation of Neurosurgical Societies (WFNS) grading that provides the highest prognostic accuracy for short- and long-term outcomes in aneurysmal subarachnoid hemorrhage (aSAH). METHODS In this cohort study of 389 patients, WFNS grades were recorded at first med...

Sebastian L Wyss, J. Fierstra, V. Staartjes et al. · Neurocritical Care · 0 citations

Review Open access Sep 2026

Advances in hypoxia-modulated blood oxygen level-dependent MRI: a narrative review of physiological principles and applications for glioblastoma imaging.

Glioma imaging remains constrained by the limited ability of conventional MRI to capture biologically relevant tumor features beyond blood-brain barrier disruption. Hypoxia-modulated blood oxygen level-dependent (BOLD) MRI has emerged as a potential contrast-agent-free approach to probe oxygenation-related tumor physio...

T. Schmidlechner, V. Stumpo, E. Jehli et al. · MAGMA · 0 citations