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Author

J. Fu

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Open access Sep 2026

Quantitative μ-Opioid Receptor PET with [18F]FCFN in Nonhuman Primates: Naloxone Blockade and Within-Scan Displacement

Background/Objectives: Quantitative PET imaging of μ-opioid receptor (MOR) availability and pharmacologic engagement can advance in vivo studies of opioid receptor biology. We previously evaluated a series of 18F-labeled carfentanil analogs and prioritized the regioisomer [18F]fluorocarfentanil ([18F]FCFN) based on fav...

Evan Gallagher, Joseph W. Downey, Chi-Hyeon Yoo et al. · 0 citations
Open access Jul 2026

Functional segregation in Parkinson’s disease

The basal ganglia are characterized by somatotopic representation and are organized in parallel, functionally segregated corticostriatal circuits, but the impact of Parkinson’s disease (PD) on this architecture is unknown, and both anatomical and functional segregation were lost in PD.

Dong-Ning Su, J. Hanania, Alexandra Pavel et al. · 0 citations

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