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Author

J. Gamarra

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2 papers indexed here

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Open access Sep 2026

Manganese availability determines insulin sensitivity by enhancing Akt activity

Insulin signaling is a critical determinant of metabolic health, and impairments in insulin action contribute to the development of type 2 diabetes. The kinase Akt is a central mediator of insulin signaling and is required for insulin’s suppression of hepatic glucose output. Although the regulation of Akt by the insuli...

J. Gamarra, Sei Higuchi, Timothy L. Yuan et al. · 0 citations
Open access Oct 2026

Manganese availability determines hepatic insulin sensitivity by enhancing Akt activity.

Insulin signaling is a critical determinant of metabolic health, and impairments in insulin action contribute to the development of type 2 diabetes. The kinase Akt is a central mediator of insulin signaling and is required for insulin's suppression of hepatic glucose output. Although the regulation of Akt by the insuli...

J. Gamarra, Sei Higuchi, Timothy L. Yuan et al. · 0 citations

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