Author

J. Garces

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Open access Sep 2026

Multi-target blood test for hepatocellular carcinoma early detection: a cross-sectional analysis of the prospective ALTUS study.

BACKGROUND & AIMS Globally, 350 million people are at risk for HCC. Ultrasound screening is recommended but is limited by poor early-stage sensitivity and low adherence. This study evaluated whether the multi-target HCC blood test (mt-HBT) demonstrates non-inferior sensitivity for early-stage HCC compared with ultrasou...

Binu V. John, M. Camardo, A. Singal et al. · Journal of Hepatology · 0 citations

Open access Oct 2026

Performance of a multi-biomarker class, multi-cancer early detection (MCED) blood test in a prospectively collected cohort.

BACKGROUND Multi-biomarker blood tests have the potential to detect a broad range of cancer types and stages. Herein, we assessed the performance of a methylation and protein (MP) classifier using samples from a large, multi-center, prospectively collected case-control study. As part of the assay development process, w...

Vladimir G. Gainullin, Mael Manesse, Fang-Lei Zhuang et al. · Cancer Epidemiology, Biomark... · 0 citations

Open access Sep 2026

Evaluation of a Tumor-Informed Molecular Residual Disease Assay in Early Triple-Negative Breast Cancer Treated With Neoadjuvant Chemotherapy, With or Without Atezolizumab

PURPOSE Detection of molecular residual disease (MRD) using circulating tumor DNA (ctDNA) is strongly associated with recurrence risk in early triple-negative breast cancer (TNBC). Prior studies suggest that ctDNA clearance during neoadjuvant therapy (NAT) may predict pathologic complete response (pCR) and enhance the...

M. Balić, G. Tang, P. Rastogi et al. · JCO Precision Oncology · 0 citations