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Author

J. García-Pedrero

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Open access Sep 2026

pTINCR Expression Is Associated with Tumor Aggressiveness but Does Not Independently Predict Prognosis in Head and Neck Cutaneous Squamous Cell Carcinoma

Terminal differentiation-induced non-coding RNA (TINCR), initially classified as a long non-coding RNA, encodes a biologically active microprotein (pTINCR) involved in epidermal differentiation and tumor biology. However, the clinicopathological and prognostic relevance of pTINCR expression in cutaneous squamous cell c...

Raquel Santos-Juanes, J. Santos-Juanes, Noelia Blanco-Agudín et al. · 0 citations
Open access Aug 2026

NGFR-driven suppression of antigen presentation limits CD8+ T cell immunity and response to checkpoint blockade

Immune checkpoint blockade has revolutionized cancer therapy; however, numerous tumors remain resistant by adopting cellular states that impede immune recognition. In this study, we identify the nerve growth factor receptor (NGFR) as a regulator of immune evasion in head and neck squamous cell carcinoma (HNSCC). Geneti...

J. García-Agulló, V. Santos, B. Majem et al. · 0 citations
Open access Aug 2026

Functional proteomics identifies targetable cancer-associated fibroblast programs in head and neck cancer

These findings define functionally distinct and pharmacologically targetable CAF programs in HNSCC and support stromal-directed interventions as a rational component of future combination treatment strategies.

Llara Prieto-Fernández, A. Martínez-Carrillo, L. de Villalaín et al. · 0 citations

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