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J. Guimarães

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Open access Sep 2026

Successful long-term control of lanadelumab-refractory type 2 hereditary angioedema with berotralstat

Type 2 hereditary angioedema (HAE-C1INH-Type2) is a rare, potentially life-threatening disorder characterized by functional impairment of C1-esterase inhibitor (C1-INH). Responses to long-term prophylactic (LTP) therapies are variable. We describe a case of HAE-C1INH-Type2 refractory to tranexamic acid, danazol, C1-INH...

J. Guimarães, J. Marcelino, I. Didenko et al. · 0 citations

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