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J. Heng

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Open access Sep 2026

The Effect of Protecting Groups and Peptide Chain Length on the Aqueous Solubility of l‑Alanine Homopeptides

The solubility of peptides is a critical physicochemical parameter governing both upstream solid-phase peptide synthesis (SPPS) route optimization and downstream crystallization design. In this study, the aqueous solubility of l-alanine and its homologous oligopeptides bearing Boc and Cbz N-terminal protecting groups w...

Jia-Ning Li, Vivek Verma, J. Heng · 0 citations

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