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Jung Joo Hong

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Open access Aug 2026

Apex-guided HIV vaccination: liposome-displayed Env trimers elicit PG9-like cross-neutralizing antibodies

In a recent Nature study, Guenaga et al. demonstrated that sequential immunization with heterologous NFL-stabilized HIV envelope (Env) trimers displayed on liposomes elicited PG9-like apex-directed cross-neutralizing serum IgG responses in all six immunized rhesus macaques, with neutralization breadth reaching up to 70...

Eun-Ha Hwang, J. Hong · 0 citations
Open access Aug 2026

Dose-dependent effects of recombinant spike protein-based vaccination on SARS-CoV-2 evolutionary dynamics and the emergence of variants in hamster models

Investigating the evolutionary dynamics of the SARS-CoV-2 Delta variant in hamsters immunized with varying doses of a full-length spike protein vaccine indicates that heterogeneous vaccine-induced immune pressure can shape intra-host SARS-CoV-2 evolution in a dose-dependent and host-specific manner and highlights the p...

Kyuyoung Shim, J. Choi, Eun-Ha Hwang et al. · 0 citations

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