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Author

J. Hung

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Open access Jul 2026

Targeting the KRAS G12D mutant suppresses tumor growth in a syngeneic mouse cholangiocarcinoma model through activation of immune cells 2258895

The in vitro proliferation of AKP-M4 cells, but not KRAS wild-type SNU-1079 and SSP-25 cells, was reduced by the KRAS G12D mutation inhibitor MRTX-1133, which supports the development of KRAS mutation inhibitor for CCA treatment.

J. Hung, Tsai-Hsien Hung, Chun-Nan Yeh et al. · 0 citations