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Author

Jun-ichi Iga

2 papers indexed here

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Open access Sep 2026

Prevalence of Treatment‐Resistant Schizophrenia: A Nationwide Multicenter Study

ABSTRACT Background Schizophrenia is characterized by positive symptoms, negative symptoms, and cognitive impairment and is primarily treated with antipsychotic medications. However, a subset of patients responds inadequately to treatment and is classified as having treatment‐resistant schizophrenia (TRS). The prevalen...

Yusuke Arai, Toru Horinouchi, Hiroyuki Muraoka et al. · 0 citations
Aug 2026

Altered IRF1-miR-20a-5p regulatory axis in the hippocampus of patients with major depressive disorder.

AIM Neuroinflammation has been implicated in the pathogenesis of major depressive disorder (MDD), with interferon regulatory factor 1 (IRF1) playing a potential role. MicroRNAs (miRs) are also involved in MDD through posttranscriptional regulation of gene expression. This study investigated whether miR-20a-5p regulates...

Mariko Okano, Yuta Yoshino, Anuj K. Verma et al. · 0 citations

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