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J. Ito

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Open access Aug 2026

A rapidly deployable CRISPR–Cas3 diagnostic platform for emerging RNA viruses

Rapidly converting viral genome information into deployable molecular tests remains a major challenge in outbreak preparedness. We developed CONAN-SWIFT (Simple Workflow for Isothermal Field Testing), a sequence-to-test platform that integrates computational assay design, reverse-transcription loop-mediated isothermal...

Jun Nakamura, Kaya Miyazaki-Iida, Shotaro Torii et al. · 0 citations
Review Open access Jul 2026

From sites to structure to serology: a roadmap for structure-aware molecular evolution of antigenically evolving viruses

A practical framework linking sites, structure, and serology for viruses in which antigenic evolution is a major component of immune escape and lineage turnover is outlined and how integrating genomic surveillance data, phylogenetics, structural analysis, and predictive modeling could support more prospective variant a...

Sanni Översti, Spyros Lytras, Shusuke Kawakubo et al. · 0 citations

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