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J. Jimenez-shahed

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Open access Oct 2026

Timing of Deep Brain Stimulation and Cognitive Trajectories in GBA1-Associated Parkinson's Disease.

BACKGROUND Individuals with Parkinson's disease (PD) carrying GBA1 variants often develop advanced motor complications that prompt evaluation for deep brain stimulation (DBS). However, concerns about accelerated cognitive decline after DBS in GBA1 carriers complicate clinical decision making. A critical aspect that is...

E. Asimakidou, M. Avenali, J. Aasly et al. · 0 citations
Open access Aug 2026

Reduced Left vmPFC-STN-Related White Matter Integrity Is Associated with Pre-Surgical Apathy in Parkinson's Disease.

Clinical significant apathy in PD prior to STN-DBS is associated with reduced white matter integrity in the left internal capsule involving the broader left-sided vmPFC projection system, which may contribute to future optimization of apathy management with STN-DBS.

Jip de Bruin, B. Kopell, H. Mayberg et al. · 0 citations

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