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Review Open access Aug 2026

Cancer Risk in Premature Ovarian Insufficiency: Current Evidence and Clinical Implications

A BSTRACT Premature ovarian insufficiency (POI), defined as loss of ovarian function before 40 years with elevated gonadotropins and oligo/amenorrhea, is increasingly recognized as a systemic condition with long-term health consequences. While cardiovascular, skeletal, and neurocognitive risks are well establishe...

Vinoth Gnana Chellaiyan Devanbu, J. John, K. Karpagam · 0 citations

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