BACKGROUND
SGLT2 inhibitors (SGLT2i) reduce mortality in left heart failure. In pulmonary arterial hypertension (PAH), preclinical data suggest SGLT2i improve right ventricular function through metabolic modulation and inhibition of vascular remodeling via smooth muscle cell pathways. The DAPAH trial evaluated whether...
M. Ersbøll, J. Kjærgaard, K. Waidtløw et al.· The Journal of Heart and Lun...· 1 citation
INTRODUCTION
In patients who survive out-of-hospital cardiac arrest (OHCA), guidelines for implantation of an implantable cardioverter-defibrillator (ICD) are not unequivocal.
METHODS
Patients resuscitated from OHCA of cardiac cause, without a reversible cause and an expected survival >1 year were identified (year 20...
M. Winther-Jensen, B. T. Philbert, M. L. Laursen et al.· Scandinavian Cardiovascular...· 0 citations
No single variable was consistently associated with prognosis or treatment response, although low SvO2 and elevated pulmonary artery pressure were associated with worse outcomes, although low SvO2 and elevated pulmonary artery pressure were associated with worse outcomes in some studies.
J. Grand, F. Lau, C. Hassager et al.· Resuscitation· 1 citation
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