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Author

J. Kuipers

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Open access Aug 2026

Reliable single-cell perturbations explain and improve model performance

This work tests the reliability of perturbations and their alignment with shared perturbation responses, classifying each perturbation as specific, shared, or unreliable, and applies these quality labels to published benchmarks shows that model comparisons depend on perturbation quality.

Xi Wang, J. Kuipers, Florian Hugi et al. · 0 citations
Preprint Sep 2026

Numerical approximations of population size distributions for multi-type branching processes

Two numerical approximations of population size distributions for multi-type branching processes on directed graphs on directed graphs with arbitrary initialization are introduced and provided computational building blocks for future likelihood-based inference in cancer evolution and other expanding populations.

Xiang-Ge Luo, J. Kuipers, N. Beerenwinkel · 0 citations

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