J. L. Klotz

312. 5-hydroxytryptophan Alleviates Toxic Fescue-induced Disruption of Fetal Muscle Development and Associated Gene Expression Pathways During Late Gestation.

Fescue toxicosis is a condition in livestock caused by the ingestion of ergot alkaloids in toxic endophyte-infected tall fescue. Ergot alkaloids induce vasoconstriction through smooth muscle contraction, reducing blood flow and resulting in uteroplacental vasoconstriction that can impair fetal growth, skeletal muscle...