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J. Leal

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Review Open access Sep 2026

Elevated Levels of Blood Neurofilament Light Chain in Substance-Using Populations: A Systematic Review and Meta-Analysis.

Substance-use disorders are increasingly linked to structural and functional brain alterations consistent with neuroaxonal injury. Neurofilament light chain (NfL) is a sensitive blood-based marker of axonal damage, but evidence in substance-using populations remains fragmented. We systematically reviewed and meta-analy...

J. Leal, T. Viola, Rodrigo Grassi-Oliveira · 0 citations

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