J. Lee

Impaired Glur2 Palmitoylation in Cerebellar Purkinje Cells of a Friedreich Ataxia Mouse Model

Friedreich’s ataxia (FRDA) is a neurodegenerative disorder caused by frataxin deficiency, characterized by progressive cerebellar dysfunction and neuronal loss. Although synaptic abnormalities are an early feature of FRDA, the molecular mechanisms linking frataxin deficiency to synaptic dysfunction remain incompletely...