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J. López

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Open access Aug 2026

Isoform-Specific Modulation of PI3K/Akt1 Signaling by Orai Channels in Estrogen Receptor-Positive Breast Cancer.

The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is a fundamental intracellular axis that integrates extracellular stimuli to orchestrate essential cellular processes. The activation of Akt1 represents a key determinant of aggressiveness in estrogen receptor positive (ER+) breast cancer, a process closely ass...

Alvaro Macías-Díaz, J. López, Manuel Fuentes-Mateos et al. · 0 citations

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