Open access
Sep 2026
RpS19a depletion alters the hematopoietic translatome to drive tissue overgrowth
It is demonstrated that RpS19a depletion directly drives excess proliferation and tissue overgrowth in the Drosophila lymph gland, suggesting that dNep1 enables assembly of pro-proliferative ribosomes essential for blood lineage overgrowth driven by ribosomal protein loss.
Naomi C. Mitchell, Arjun S. Chahal, T. Javaid et al.
· iScience · 0 citations