J. Lorenzo-Morales

Synthesis of polysubstituted lactones and apoptotic hallmarks in Naegleria fowleri: Exploring their potential as amoebicidal agents.

Naegleria fowleri is the etiological agent of primary amoebic meningoencephalitis, a fulminant infection of the central nervous system that leads to death in most cases. Currently, no standardised therapy is available, and existing treatments are limited by inconsistent efficacy and significant toxicity. β-Hydroxy-γ-la...