Author

J. Luque‐Garcia

2 papers indexed here

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Open access Jul 2026

Systems-Level Multi-Omics Analysis Resolves the Mechanism of Action of a Novel Multifunctional Nanosystem Against Triple-Negative Breast Cancer

The integration of multi-omics data revealed the activation of compensatory mechanisms aimed at restoring cellular homeostasis, including metabolic rewiring and stress-response pathways, although these responses were insufficient to counteract nanosystem-induced cytotoxicity.

M. P. Buendia-Nacarino, Dominik Bulfon, Nikola Tom et al. · Pharmaceutics · 1 citation

Open access Aug 2026

Therapeutic transformation of a rhodium nanophotosensitizer into a tamoxifen-loaded targeted nano-drug for dual chemo-photodynamic therapy of ER-positive breast cancer.

This work establishes a mechanistically informed dual-modality nano-drug that expands the therapeutic scope of rhodium nanophotosensitizers beyond conventional PDT, providing a new strategy for targeted treatment of ER-positive breast cancer.

Andres Machuca, Alejandro García García, Estefanía García-Calvo et al. · Colloids and Surfaces B: Bio... · 0 citations