Open access
Aug 2026
Non-cell autonomous control of presynaptic remodeling by the hypothalamic autophagy-NPY axis.
Macroautophagy/autophagy is a critical cellular degradation pathway essential for neuronal proteostasis and synaptic function. Its decline with aging is associated with synaptic dysfunction and reduced circuit resilience. NPY (neuropeptide Y), a highly abundant brain neuropeptide, has emerged as an important regulator...
Giovanna Cazzolla, David Toppe, Gina Krause et al.
· Autophagy · 0 citations