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Open access Sep 2026

Plasma P-tau217, APOE Genotype, and the Timing of Cognitive Impairment in individuals Across Diverse Racial and Ethnic Groups: A Pooled Analysis of Prospective Cohort Studies

ABSTRACT/SUMMARY Background: Plasma phosphorylated tau217 (P-tau217), a biomarker of Alzheimer’s disease (AD), can increase before overt symptoms. However, individuals with similar P-tau217 levels but different genetic backgrounds might differ in their risk or timing of cognitive decline. We aimed to determine whether...

Yue-Xuan Xu, T. I. Gunasekaran, Yian Gu et al. · 0 citations
Aug 2026

Episodic memory abilities predict lexical diversity in spontaneous speech across languages and the adult lifespan

Previous research has linked episodic memory to word learning and processing, but its role in broader lexical behaviors, such as lexical diversity, is still not well-understood. The present study leveraged existing data from a community-based sample of 564 adults (ages 27–89) who completed an episodic memory task a...

Phillip Hamrick, John Gunstad, Kate McClure et al. · 0 citations

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