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J. Meijers

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Review Open access Sep 2026

A Beginner's Guide to Study the Role of Extracellular Vesicles in Coagulation

ABSTRACT This guide provides an overview of information that is needed to understand and study the coagulant functions of extracellular vesicles (EVs) in human body fluids. Although EV research has expanded rapidly, the physiological functions of EVs remain incompletely understood, and coagulation is one of the first b...

R. Nieuwland, Jillian W. P. Bracht, J. Meijers et al. · 0 citations

CHAPTER 4 The HSPG binding domain of APRIL serves as a platform for ligand multimersation and cross-linking.

It is shown that the lack of HSPG interaction can be compensated by artificial cross-linking, which indicates that the HSPG-binding domain in APRIL is not necessary to allow for signalling through HSPG, but instead mediates ligand cross-linking and oligomerisation.

Fiona C. Kimberley, Liesbeth van Bostelen, Gijs Hardenberg et al. · 0 citations

Inhibitionn of the tissue factor pathway of coagulation by recombinantt nematode anticoagulant protein c2 in patientss undergoing elective coronary stent implantation: effectss on hemostatic and inflammatory parameters

Whether inhibition of TF-factor Vilaa by recombinant Nematode Anticoagulant Protein c2 (rNAPc2) is able to suppresss hemostatic and inflammatory activity in patients undergoing elective intracoronaryy stenting is investigated.

A. Moons, N. R. Bijsterveld, J. Meijers et al. · 0 citations

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