Open access
Oct 2026
The mammalian genome is punctuated by regularly spaced nucleosome islands
Nucleosome positioning plays a fundamental role in regulating DNA accessibility and cellular activity, yet the precise rules by which mammalian sequences instruct this organization have remained incomplete. Prior work has established that intrinsic sequence preferences dictate nucleosome architecture in yeast, but in m...
M. Christophe, L. Altamirano, P. Navarro et al.
· bioRxiv · 0 citations