Ketamine Alters Tuning of Neural and Behavioral Spatial Working Memory Precision.
BACKGROUND Working memory (WM) is a key element of cognition that depends on accurate internal representation of stimuli and often impaired in psychiatric disorders, including schizophrenia. Prior human neuropharmacological studies with ketamine suggest that glutamate N-methyl-D-aspartate receptors (NMDARs) are critica...