Open access
Aug 2026
Genome-wide CRISPR-screening identifies p53 as regulator of cancer cell sensitivity to the histone evicting anthracycline aclarubicin
A genome-wide CRISPR screen to identify factors regulating sensitivity of cells to aclarubicin and identified p53 as a critical factor for cellular sensitivity suggests p53 could be an important factor to stratify patients for treatment with Aclarubicin.
Sabina Y. van der Zanden, Koen Schipper, Merle A. van Gelder et al.
· Cell Death & Disease · 0 citations